林冬菊，女，博士，讲师，硕士生导师。2017年毕业于沈阳药科大学药物分析专业，同年，进入河北大学药学院工作。研究方向为药物代谢、药代动力学、药物毒理研究。近年来，在Drug Metab. Dispos.，Chem. Res. Toxicol.，Toxicol. Lett.等国际学术期刊发表SCI论文多篇。

联系方式：E-mail:lindo.ngju@163.com

主讲课程及研究方向

1. 主讲课程：药剂学

2. 研究方向：药物代谢、药代动力学、药物毒理研究

承担科研项目

河北省自然科学基金，H2019201360，基于CYP酶研究甘草次酸对黄独素B肝毒性的保护作用，2019/01-2021/12，在研，主持。

代表性论文

Lin DJ^*, Ma Q, Zhang YW, Peng ZY. Phenolic compounds with antioxidant activity from strawberry leaves: a study on microwave-assisted extraction optimization. Prep. Biochem. Biotechnol. 2020, 50: 874-882.

Lin DJ, Li WW, Tian XT, Peng Y, Zheng J^*. In Vitro DNA Adduction Resulting from Metabolic Activation of Diosbulbin B and 8-Epidiosbulbin E Acetate. Chem. Res.Toxicol. 2019, 32: 38-48.

Lin DJ, Li WW, Peng Y, Jiang CF, Xu YJ, Gao HY, Zheng J^*. Role of metabolic activation in 8-epidiosbulbin E acetate-induced liver injury: mechanism of action of the hepatotoxic furanoid. Chem. Res. Toxicol. 2016, 29: 359–366.

Lin DJ, Wang K, Guo XC, Peng Y, Zheng J^*. Lysine- and Cysteine-based Protein Adductions Derived from Toxic Metabolites of 8-Epidiosbulbin E Acetate. Toxicol.Lett. 2016, 264: 20-28.

Li WW，Lin DJ, Gao HY, Xu Y, Meng D, Smith CV, Peng Y, Zheng J^*. Metabolic Activation of Furan Moiety Makes Diosbulbin B Hepatotoxic. Arch. Toxicol. 2016, 90: 863-872.

Lin DJ, Guo XC, Gao HY, Cheng L, Cheng MS, Song SJ, Peng Y, Zheng J^*. In vitro and in vivo studies of the metabolic activation of 8-epidiosbulbin E acetate. Chem. Res. Toxicol. 2015, 28: 1737–1746.

Lin DJ, Li CY, Peng Y, Gao HY, Zheng J^*. Cytochrome P450-mediated metabolic activation of diosbulbin B. Drug Metab. Dispos. 2014, 42: 1727−1736.